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ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
Li, Jie; Galbo, Phillip M; Gong, Weida; Storey, Aaron J; Tsai, Yi-Hsuan; Yu, Xufen; Ahn, Jeong Hyun; Guo, Yiran; Mackintosh, Samuel G; Edmondson, Ricky D; Byrum, Stephanie D; Farrar, Jason E; He, Shenghui; Cai, Ling; Jin, Jian; Tackett, Alan J; Zheng, Deyou; Wang, Gang Greg.
Affiliation
  • Li J; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Galbo PM; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Gong W; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Storey AJ; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Tsai YH; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Yu X; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Ahn JH; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Guo Y; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Mackintosh SG; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Edmondson RD; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Byrum SD; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Farrar JE; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • He S; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Cai L; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Jin J; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Tackett AJ; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock, AR, USA.
  • Zheng D; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
  • Wang GG; Department of Genetics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Nat Commun ; 12(1): 1045, 2021 02 16.
Article in En | MEDLINE | ID: mdl-33594072
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Chromosomal Proteins, Non-Histone / Leukemia, Myeloid, Acute / Cell Cycle Proteins / DNA-Binding Proteins / Co-Repressor Proteins / Lysine Acetyltransferase 5 Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Chromosomal Proteins, Non-Histone / Leukemia, Myeloid, Acute / Cell Cycle Proteins / DNA-Binding Proteins / Co-Repressor Proteins / Lysine Acetyltransferase 5 Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: