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Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21).
Burlet, Bénédicte; Ramla, Selim; Fournier, Cyril; Abrey-Recalde, Maria Jimena; Sauter, Camille; Chrétien, Marie-Lorraine; Rossi, Cédric; Duffourd, Yannis; Ragot, Sylviane; Buriller, Céline; Tournier, Benjamin; Chapusot, Caroline; Nadal, Nathalie; Racine, Jessica; Guy, Julien; Bailly, François; Martin, Laurent; Casasnovas, Olivier; Bastie, Jean-Noël; Caillot, Denis; Albuisson, Juliette; Broccardo, Cyril; Thieblemont, Catherine; Delva, Laurent; Maynadié, Marc; Aucagne, Romain; Callanan, Mary B.
Affiliation
  • Burlet B; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Ramla S; Unit for innovation in genetics and epigenetics in oncology, Dijon University Hospital, 21079 Dijon, France.
  • Fournier C; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Abrey-Recalde MJ; Department of Pathology, Dijon University Hospital, 21079 Dijon, France.
  • Sauter C; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Chrétien ML; Unit for innovation in genetics and epigenetics in oncology, Dijon University Hospital, 21079 Dijon, France.
  • Rossi C; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Duffourd Y; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Ragot S; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Buriller C; Hematology Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Tournier B; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Chapusot C; Department of Clinical Hematology, Dijon University Hospital, 21079 Dijon, France.
  • Nadal N; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Racine J; Unit for innovation in genetics and epigenetics in oncology, Dijon University Hospital, 21079 Dijon, France.
  • Guy J; Genetics Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Bailly F; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Martin L; Unit for innovation in genetics and epigenetics in oncology, Dijon University Hospital, 21079 Dijon, France.
  • Casasnovas O; Department of Pathology, Dijon University Hospital, 21079 Dijon, France.
  • Bastie JN; Department of Pathology, Dijon University Hospital, 21079 Dijon, France.
  • Caillot D; Genetics Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Albuisson J; Hematology Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Broccardo C; Hematology Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Thieblemont C; Hematology Laboratory, Dijon University Hospital, 21079 Dijon, France.
  • Delva L; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Maynadié M; Department of Pathology, Dijon University Hospital, 21079 Dijon, France.
  • Aucagne R; University of Burgundy-ISITE-BFC-Institut national de la santé et de la recherche médicale (Inserm) UMR1231, Faculty of Medicine, 21079 Dijon, France.
  • Callanan MB; Department of Clinical Hematology, Dijon University Hospital, 21079 Dijon, France.
Cold Spring Harb Mol Case Stud ; 7(1)2021 02.
Article in En | MEDLINE | ID: mdl-33608382
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Leukemia, Lymphocytic, Chronic, B-Cell / Homeodomain Proteins / Cell Cycle Proteins / Epigenesis, Genetic / Proto-Oncogene Proteins B-raf / PAX5 Transcription Factor / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Aged / Humans / Male Language: En Journal: Cold Spring Harb Mol Case Stud Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Leukemia, Lymphocytic, Chronic, B-Cell / Homeodomain Proteins / Cell Cycle Proteins / Epigenesis, Genetic / Proto-Oncogene Proteins B-raf / PAX5 Transcription Factor / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Aged / Humans / Male Language: En Journal: Cold Spring Harb Mol Case Stud Year: 2021 Document type: Article Affiliation country: