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Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.
Peng, Hongzhuang; Cassel, Joel; McCracken, Daniel S; Prokop, Jeremy W; Sementino, Eleonora; Cheung, Mitchell; Collop, Paul R; Polo, Alexander; Joshi, Surbhi; Mandell, Jacob P; Ayyanathan, Kasirajan; Hinds, David; Malkowicz, S Bruce; Harbour, J William; Bowcock, Anne M; Salvino, Joseph; Kennedy, Eileen J; Testa, Joseph R; Rauscher, Frank J.
Affiliation
  • Peng H; The Wistar Institute, Philadelphia, Pennsylvania. joseph.testa@fccc.edu hongzhuangpeng851@gmail.com.
  • Cassel J; The Wistar Institute, Philadelphia, Pennsylvania.
  • McCracken DS; The Wistar Institute, Philadelphia, Pennsylvania.
  • Prokop JW; Department of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Sementino E; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan.
  • Cheung M; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan.
  • Collop PR; Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Polo A; Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Joshi S; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia.
  • Mandell JP; The Wistar Institute, Philadelphia, Pennsylvania.
  • Ayyanathan K; The Wistar Institute, Philadelphia, Pennsylvania.
  • Hinds D; The Wistar Institute, Philadelphia, Pennsylvania.
  • Malkowicz SB; The Wistar Institute, Philadelphia, Pennsylvania.
  • Harbour JW; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan.
  • Bowcock AM; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan.
  • Salvino J; Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Kennedy EJ; University of Miami School of Medicine, Miami, Florida.
  • Testa JR; Icahn School of Medicine at Mount Sinai, New York, New York.
  • Rauscher FJ; The Wistar Institute, Philadelphia, Pennsylvania.
Mol Cancer Res ; 19(7): 1099-1112, 2021 07.
Article in En | MEDLINE | ID: mdl-33731362

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Tumor Suppressor Proteins / Ubiquitin Thiolesterase / Allosteric Regulation Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Tumor Suppressor Proteins / Ubiquitin Thiolesterase / Allosteric Regulation Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2021 Document type: Article