Feasibility of ultrashort echo time (UTE) T2* cartilage mapping in the hip: a pilot study.
Acta Radiol
; 63(6): 760-766, 2022 Jun.
Article
in En
| MEDLINE
| ID: mdl-33926266
ABSTRACT
BACKGROUND:
Ultrashort echo time (UTE) T2* is sensitive to molecular changes within the deep calcified layer of cartilage. Feasibility of its use in the hip needs to be established to determine suitability for clinical use.PURPOSE:
To establish feasibility of UTE T2* cartilage mapping in the hip and determine if differences in regional values exist. MATERIAL ANDMETHODS:
MRI scans with UTE T2* cartilage maps were prospectively acquired on eight hips. Hip cartilage was segmented into whole and deep layers in anterosuperior, superior, and posterosuperior regions. Quantitative UTE T2* maps were analyzed (independent one-way ANOVA) and reliability was calculated (ICC).RESULTS:
UTE T2* mean values (anterosuperior, superior, posterosuperior) full femoral layer (19.55, 18.43, 16.84 ms) (P=0.004), full acetabular layer (19.37, 17.50, 16.73 ms) (P=0.013), deep femoral layer (18.68, 17.90, 15.74 ms) (P=0.010), and deep acetabular layer (17.81, 16.18, 15.31 ms) (P=0.007). Values were higher in anterosuperior compared to posterosuperior regions (mean difference; 95% confidence interval [CI]) full femur layer (2.71 ms; 95% CI 0.91-4.51 P=0.003), deep femur layer (2.94 ms; 95% CI 0.69-5.19; P=0.009), full acetabular layer (2.63 ms 95% CI 0.55-4.72; P=0.012), and deep acetabular layer (2.50 ms; 95% CI 0.69-4.30; P=0.006). Intra-reader (ICC 0.89-0.99) and inter-reader reliability (ICC 0.63-0.96) were good to excellent for the majority of cartilage layers.CONCLUSION:
UTE T2* cartilage mapping was feasible in the hip with mean values in the range of 16.84-19.55 ms in the femur and 16.73-19.37 ms in the acetabulum. Significantly higher values were present in the anterosuperior region compared to the posterosuperior region.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cartilage, Articular
Limits:
Humans
Language:
En
Journal:
Acta Radiol
Year:
2022
Document type:
Article
Affiliation country: