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Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints.
Li Yim, Andrew Y F; Ferrero, Enrico; Maratou, Klio; Lewis, Huw D; Royal, George; Tough, David F; Larminie, Chris; Mannens, Marcel M A M; Henneman, Peter; de Jonge, Wouter J; van de Sande, Marleen G H; Gerlag, Danielle M; Prinjha, Rab K; Tak, Paul P.
Affiliation
  • Li Yim AYF; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Ferrero E; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • Maratou K; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Lewis HD; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Royal G; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Tough DF; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Larminie C; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Mannens MMAM; R&D GlaxoSmithKline, Stevenage, United Kingdom.
  • Henneman P; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • de Jonge WJ; Department of Clinical Genetics, Genome Diagnostics Laboratory, Amsterdam Reproduction & Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • van de Sande MGH; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology & Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • Gerlag DM; Department of Surgery, University Clinic of Bonn, Bonn, Germany.
  • Prinjha RK; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and Immunology Center, Amsterdam Institute for Infection & Immunity, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • Tak PP; Department of Experimental Immunology, Amsterdam Institute for Infection & Immunity, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
Front Immunol ; 12: 651475, 2021.
Article in En | MEDLINE | ID: mdl-33968050
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Membrane / Arthralgia / DNA Methylation / Epigenesis, Genetic Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Front Immunol Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Membrane / Arthralgia / DNA Methylation / Epigenesis, Genetic Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Front Immunol Year: 2021 Document type: Article Affiliation country: Country of publication: