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The ERRα-VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR-CYP24A1-ERRα overexpression correlates with poor prognosis in patients with basal-like breast cancer.
Danza, Katia; Porcelli, Letizia; De Summa, Simona; Di Fonte, Roberta; Pilato, Brunella; Lacalamita, Rosanna; Serratì, Simona; Azzariti, Amalia; Tommasi, Stefania.
Affiliation
  • Danza K; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Porcelli L; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • De Summa S; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Di Fonte R; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Pilato B; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Lacalamita R; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Serratì S; Laboratory of Nanotechnology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Azzariti A; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Tommasi S; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
Mol Oncol ; 16(4): 904-920, 2022 02.
Article in En | MEDLINE | ID: mdl-34003583
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Calcitriol Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptors, Calcitriol Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2022 Document type: Article Affiliation country: Country of publication: