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Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade.
Yan, Chi; Saleh, Nabil; Yang, Jinming; Nebhan, Caroline A; Vilgelm, Anna E; Reddy, E Premkumar; Roland, Joseph T; Johnson, Douglas B; Chen, Sheau-Chiann; Shattuck-Brandt, Rebecca L; Ayers, Gregory D; Richmond, Ann.
Affiliation
  • Yan C; Department of Veterans Affairs, Tennessee Valley Healthcare System, 432 PRB, 2220 Pierce Ave, Nashville, TN, 37232, USA.
  • Saleh N; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Yang J; Department of Veterans Affairs, Tennessee Valley Healthcare System, 432 PRB, 2220 Pierce Ave, Nashville, TN, 37232, USA.
  • Nebhan CA; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Vilgelm AE; Department of Veterans Affairs, Tennessee Valley Healthcare System, 432 PRB, 2220 Pierce Ave, Nashville, TN, 37232, USA.
  • Reddy EP; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Roland JT; Department of Veterans Affairs, Tennessee Valley Healthcare System, 432 PRB, 2220 Pierce Ave, Nashville, TN, 37232, USA.
  • Johnson DB; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA.
  • Chen SC; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Shattuck-Brandt RL; Department of Pathology, The Ohio State University, Columbus, OH, USA.
  • Ayers GD; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Richmond A; Departments of Surgery and Pediatrics and the Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Mol Cancer ; 20(1): 85, 2021 06 06.
Article in En | MEDLINE | ID: mdl-34092233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Ras Proteins / CD40 Antigens / Immune Checkpoint Inhibitors / Glycine / Melanoma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2021 Document type: Article Affiliation country:
Fulltext
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Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Ras Proteins / CD40 Antigens / Immune Checkpoint Inhibitors / Glycine / Melanoma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2021 Document type: Article Affiliation country: