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Drug sensitivity profile of minor KRAS mutations in colorectal cancer using mix culture assay: The effect of AMG-510, a novel KRAS G12C selective inhibitor, on colon cancer cells is markedly enhanced by the combined inhibition of MEK and BCL-XL.
Kitazawa, Masato; Miyagawa, Yusuke; Koyama, Makoto; Nakamura, Satoshi; Hondo, Nao; Miyazaki, Satoru; Muranaka, Futoshi; Tokumaru, Shigeo; Yamamoto, Yuta; Ehara, Takehito; Kuroiwa, Masatsugu; Tanaka, Hirokazu; Komatsu, Daisuke; Takeoka, Michiko; Soejima, Yuji.
Affiliation
  • Kitazawa M; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Miyagawa Y; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Koyama M; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Nakamura S; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Hondo N; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Miyazaki S; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Muranaka F; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Tokumaru S; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Yamamoto Y; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Ehara T; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Kuroiwa M; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Tanaka H; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Komatsu D; Department of Surgery, Jinai Hospital, Ina, Nagano 396-0026, Japan.
  • Takeoka M; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
  • Soejima Y; Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
Mol Clin Oncol ; 15(1): 148, 2021 Jul.
Article in En | MEDLINE | ID: mdl-34094546
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Mol Clin Oncol Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Mol Clin Oncol Year: 2021 Document type: Article Affiliation country: