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Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharmacophore.
Barraza, Scott J; Sindac, Janice A; Dobry, Craig J; Delekta, Philip C; Lee, Pil H; Miller, David J; Larsen, Scott D.
Affiliation
  • Barraza SJ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Sindac JA; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Dobry CJ; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Delekta PC; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Lee PH; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Miller DJ; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Larsen SD; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States. Electronic address: sdlarsen@med.umich.edu.
Bioorg Med Chem Lett ; 46: 128171, 2021 08 15.
Article in En | MEDLINE | ID: mdl-34098081

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Alphavirus / Indoles Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Alphavirus / Indoles Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication: