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Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui, Celia; Plata-Gómez, Ana Belén; Deleyto-Seldas, Nerea; García, Fernando; Ortega-Molina, Ana; Abril-Garrido, Julio; Rodriguez, Elena; Nemazanyy, Ivan; Tribouillard, Laura; de Martino, Alba; Caleiras, Eduardo; Campos-Olivas, Ramón; Mulero, Francisca; Laplante, Mathieu; Muñoz, Javier; Pende, Mario; Sabio, Guadalupe; Sabatini, David M; Efeyan, Alejo.
Affiliation
  • de la Calle Arregui C; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Plata-Gómez AB; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Deleyto-Seldas N; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • García F; Proteomics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Ortega-Molina A; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Abril-Garrido J; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Rodriguez E; Myocardial Pathophysiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
  • Nemazanyy I; Platform for Metabolic Analyses, Structure Fédérative de Recherche Necker, INSERM US24/CNRS UMS 3633, Paris, France.
  • Tribouillard L; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Faculté de Médecine, Université Laval, Québec, QC, Canada.
  • de Martino A; Centre de recherche sur le cancer de l'Université Laval, Université Laval, Québec, QC, Canada.
  • Caleiras E; Histopathology Unit. Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Campos-Olivas R; Histopathology Unit. Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Mulero F; Spectroscopy and NMR Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Laplante M; Molecular Imaging Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Muñoz J; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Faculté de Médecine, Université Laval, Québec, QC, Canada.
  • Pende M; Centre de recherche sur le cancer de l'Université Laval, Université Laval, Québec, QC, Canada.
  • Sabio G; Proteomics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Sabatini DM; Institut Necker Enfants Malades, INSERM U1151, Université de Paris, Paris, France.
  • Efeyan A; Myocardial Pathophysiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Nat Commun ; 12(1): 3660, 2021 06 16.
Article in En | MEDLINE | ID: mdl-34135321
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Fasting / Monomeric GTP-Binding Proteins / Liver Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Fasting / Monomeric GTP-Binding Proteins / Liver Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: