A Systematic Review of Dietary Supplements and Alternative Therapies for Weight Loss.
Obesity (Silver Spring)
; 29(7): 1102-1113, 2021 07.
Article
in En
| MEDLINE
| ID: mdl-34159755
ABSTRACT
OBJECTIVE:
Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight loss.METHODS:
A systematic review was conducted to evaluate the efficacy of dietary supplements and alternative therapies for weight loss in participants aged ≥18 years. Searches of Medline (PubMed), Cochrane Library, Web of Science, CINAHL, and Embase (Ovid) were conducted. Risk of bias and results were summarized qualitatively.RESULTS:
Of the 20,504 citations retrieved in the database search, 1,743 full-text articles were reviewed, 315 of which were randomized controlled trials evaluating the efficacy of 14 purported dietary supplements, therapies, or a combination thereof. Risk of bias and sufficiency of data varied widely. Few studies (n = 52 [16.5%]) were classified as low risk and sufficient to support efficacy. Of these, only 16 (31%) noted significant pre/post intergroup differences in weight (range 0.3-4.93 kg).CONCLUSIONS:
Dietary supplements and alternative therapies for weight loss have a limited high-quality evidence base of efficacy. Practitioners and patients should be aware of the scientific evidence of claims before recommending use.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Complementary Therapies
/
Weight Loss
Type of study:
Clinical_trials
/
Guideline
/
Systematic_reviews
Limits:
Adolescent
/
Adult
/
Humans
Language:
En
Journal:
Obesity (Silver Spring)
Journal subject:
CIENCIAS DA NUTRICAO
/
FISIOLOGIA
/
METABOLISMO
Year:
2021
Document type:
Article
Affiliation country: