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Crystal structure of an apo 7α-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding.
Kim, Ki-Hwa; Lee, Chang Woo; Pardhe, Bashu Dev; Hwang, Jisub; Do, Hackwon; Lee, Yung Mi; Lee, Jun Hyuck; Oh, Tae-Jin.
Affiliation
  • Kim KH; Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Asan, 31460, Republic of Korea.
  • Lee CW; Research Unit of Cryogenic Novel Material, Korea Polar Research Institute, Incheon, 21990, Republic of Korea.
  • Pardhe BD; Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Asan, 31460, Republic of Korea.
  • Hwang J; Research Unit of Cryogenic Novel Material, Korea Polar Research Institute, Incheon, 21990, Republic of Korea; Department of Polar Sciences, University of Science and Technology, Incheon, 21990, Republic of Korea.
  • Do H; Research Unit of Cryogenic Novel Material, Korea Polar Research Institute, Incheon, 21990, Republic of Korea.
  • Lee YM; Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, Republic of Korea.
  • Lee JH; Research Unit of Cryogenic Novel Material, Korea Polar Research Institute, Incheon, 21990, Republic of Korea; Department of Polar Sciences, University of Science and Technology, Incheon, 21990, Republic of Korea. Electronic address: junhyucklee@kopri.re.kr.
  • Oh TJ; Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Asan, 31460, Republic of Korea; Genome-based BioIT Convergence Institute, Asan, 31460, Republic of Korea; Department of Pharmaceutical Engineering and Biotechnology, SunMoon University, Asan, 31460, Republic
J Steroid Biochem Mol Biol ; 212: 105945, 2021 09.
Article in En | MEDLINE | ID: mdl-34171491
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydroxysteroid Dehydrogenases Language: En Journal: J Steroid Biochem Mol Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2021 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydroxysteroid Dehydrogenases Language: En Journal: J Steroid Biochem Mol Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2021 Document type: Article