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The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.
Jessulat, Matthew; Amin, Shahreen; Hooshyar, Mohsen; Malty, Ramy; Moutaoufik, Mohamed Taha; Zilocchi, Mara; Istace, Zoe; Phanse, Sadhna; Aoki, Hiroyuki; Omidi, Katayoun; Burnside, Daniel; Samanfar, Bahram; Aly, Khaled A; Golshani, Ashkan; Babu, Mohan.
Affiliation
  • Jessulat M; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Amin S; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Hooshyar M; Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada.
  • Malty R; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario K1S5 B6, Canada.
  • Moutaoufik MT; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Zilocchi M; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Istace Z; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Phanse S; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Aoki H; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Omidi K; Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada.
  • Burnside D; Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada.
  • Samanfar B; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario K1S5 B6, Canada.
  • Aly KA; Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada.
  • Golshani A; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario K1S5 B6, Canada.
  • Babu M; Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada.
Nucleic Acids Res ; 49(14): 8145-8160, 2021 08 20.
Article in En | MEDLINE | ID: mdl-34244791
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic AMP-Dependent Protein Kinases / Saccharomyces cerevisiae Proteins / DNA Repair Enzymes / DNA-Binding Proteins / Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / DNA End-Joining Repair Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic AMP-Dependent Protein Kinases / Saccharomyces cerevisiae Proteins / DNA Repair Enzymes / DNA-Binding Proteins / Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / DNA End-Joining Repair Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: Country of publication: