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Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants.
Moriyama, Saya; Adachi, Yu; Sato, Takashi; Tonouchi, Keisuke; Sun, Lin; Fukushi, Shuetsu; Yamada, Souichi; Kinoshita, Hitomi; Nojima, Kiyoko; Kanno, Takayuki; Tobiume, Minoru; Ishijima, Keita; Kuroda, Yudai; Park, Eun-Sil; Onodera, Taishi; Matsumura, Takayuki; Takano, Tomohiro; Terahara, Kazutaka; Isogawa, Masanori; Nishiyama, Ayae; Kawana-Tachikawa, Ai; Shinkai, Masaharu; Tachikawa, Natsuo; Nakamura, Shigeki; Okai, Takahiro; Okuma, Kazu; Matano, Tetsuro; Fujimoto, Tsuguto; Maeda, Ken; Ohnishi, Makoto; Wakita, Takaji; Suzuki, Tadaki; Takahashi, Yoshimasa.
Affiliation
  • Moriyama S; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Adachi Y; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Sato T; Tokyo Shinagawa Hospital, Tokyo, 140-8522, Japan.
  • Tonouchi K; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan; Department of Life Science and Medical Bioscience, Waseda University, Tokyo, 162-8480, Japan.
  • Sun L; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Fukushi S; Department of Virology I, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Yamada S; Department of Virology I, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Kinoshita H; Department of Virology I, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Nojima K; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, 208-0011, Japan.
  • Kanno T; Department of Pathology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Tobiume M; Department of Pathology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Ishijima K; Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Kuroda Y; Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Park ES; Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Onodera T; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Matsumura T; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Takano T; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Terahara K; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Isogawa M; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Nishiyama A; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Kawana-Tachikawa A; AIDS Research Center, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Shinkai M; Tokyo Shinagawa Hospital, Tokyo, 140-8522, Japan.
  • Tachikawa N; Yokohama Municipal Citizen's Hospital, Kanagawa, 221-0855, Japan.
  • Nakamura S; Tokyo Medical University, Tokyo, 160-8402, Japan.
  • Okai T; Kawakita General Hospital, Tokyo, 166-0001, Japan.
  • Okuma K; Department of Safety Research on Blood and Biological Products, National Institute of Infectious Diseases, Tokyo, 208-0011, Japan.
  • Matano T; AIDS Research Center, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Fujimoto T; Center for Emergency Preparedness and Response, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Maeda K; Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Ohnishi M; National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Wakita T; National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Suzuki T; Department of Pathology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
  • Takahashi Y; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan. Electronic address: ytakahas@niid.go.jp.
Immunity ; 54(8): 1841-1852.e4, 2021 08 10.
Article in En | MEDLINE | ID: mdl-34246326
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Neutralizing / SARS-CoV-2 / COVID-19 / Antibodies, Viral Limits: Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Neutralizing / SARS-CoV-2 / COVID-19 / Antibodies, Viral Limits: Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: