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Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes, Thomas; Polyzou, Aikaterini; Prater, Pia; Morales-Hernández, Antonio; Ferrarini, Mariana Galvao; Kehrer, Natalie; Lefkopoulos, Stylianos; Bergo, Veronica; Hummel, Barbara; Obier, Nadine; Maticzka, Daniel; Bridgeman, Anne; Herman, Josip S; Ilik, Ibrahim; Klaeylé, Lhéanna; Rehwinkel, Jan; McKinney-Freeman, Shannon; Backofen, Rolf; Akhtar, Asifa; Cabezas-Wallscheid, Nina; Sawarkar, Ritwick; Rebollo, Rita; Grün, Dominic; Trompouki, Eirini.
Affiliation
  • Clapes T; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Polyzou A; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Prater P; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Sagar; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Morales-Hernández A; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Ferrarini MG; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany.
  • Kehrer N; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Lefkopoulos S; Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Bergo V; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Hummel B; Univ Lyon, INSA-Lyon, INRAE, BF2I, UMR0203, Villeurbanne, France.
  • Obier N; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Maticzka D; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Bridgeman A; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Herman JS; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Ilik I; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany.
  • Klaeylé L; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Rehwinkel J; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • McKinney-Freeman S; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany.
  • Backofen R; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Akhtar A; Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Cabezas-Wallscheid N; Department of Computer Science, University of Freiburg, Freiburg, Germany.
  • Sawarkar R; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Rebollo R; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Grün D; Würzburg Institute of Systems Immunology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
  • Trompouki E; Department of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Nat Cell Biol ; 23(7): 704-717, 2021 07.
Article in En | MEDLINE | ID: mdl-34253898
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / DNA Transposable Elements / Cellular Senescence / Myeloablative Agonists / Cell Proliferation / Interferon-Induced Helicase, IFIH1 / Hematopoiesis Limits: Animals / Humans Language: En Journal: Nat Cell Biol Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / DNA Transposable Elements / Cellular Senescence / Myeloablative Agonists / Cell Proliferation / Interferon-Induced Helicase, IFIH1 / Hematopoiesis Limits: Animals / Humans Language: En Journal: Nat Cell Biol Year: 2021 Document type: Article Affiliation country: