mpMRI PI-RADS score 3 lesions diagnosed by reference vs affiliated radiological centers: Our experience in 950 cases.
Arch Ital Urol Androl
; 93(2): 139-142, 2021 Jun 28.
Article
in En
| MEDLINE
| ID: mdl-34286544
ABSTRACT
INTRODUCTION:
The detection rate for clinically significant prostate cancer (csPCa) in men with mpMRI PI-RADS score 3 diagnosed by affiliated radiology centers vs radiological reference center was evaluated. MATERIALS ANDMETHODS:
From January 2017 to December 2020, 950 men (median age 64 years) underwent mpMRI for abnormal PSA values (median 6.3 ng/ml). Among the 950 patients who underwent mpMRI 500 were evaluated by a reference center and 450 by outpatient radiological affiliated centers. All the mpMRI index lesions characterized by a PI-RADS 3 underwent targeted cores combined with extended prostate biopsy. Two radiologists of the radiological reference center revised all the mpMRI lesions 3.RESULTS:
Overall, 361/950 (38%) patients had a mpMRI lesion PI-RADS score 3 120/500 cases (24%) vs 241/450 cases (53.5%) were diagnosed by reference vs affiliated radiological centers. The detection rate for cT1c csPCa was equal to 26.7% (35/120 cases) vs 16.6% (40/241 cases) in men with PI-RADS 3 lesions diagnosed in the reference vs the affiliated radiological centers (p < 0.05). Among the 241 PI-RADS score 3 lesions diagnosed by affiliated radiological centers 86/241 (35.7%) and 36/241 (15%) were downgraded (PI-RADS scores < 3) and upgraded (PI-RADS score 4) by the dedicated radiologists of the reference center.CONCLUSIONS:
In our series, about 35% and 15% of PI-RADS score 3 lesions diagnosed by affiliated radiological centers were downgraded and upgraded when revised by experencied radiologists, therefore a second opinion is mandatory especially in men enrolled in active surveillance protocols in whom mpMRI is recommended to reduce the number of scheduled repeated prostate biopsies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatic Neoplasms
/
Radiology
/
Multiparametric Magnetic Resonance Imaging
Type of study:
Diagnostic_studies
/
Guideline
/
Observational_studies
Limits:
Humans
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Male
/
Middle aged
Language:
En
Journal:
Arch Ital Urol Androl
Journal subject:
MEDICINA REPRODUTIVA
/
NEFROLOGIA
/
UROLOGIA
Year:
2021
Document type:
Article
Publication country:
IT
/
ITALIA
/
ITALY
/
ITÁLIA