Structural basis of human separase regulation by securin and CDK1-cyclin B1.

Yu, Jun; Raia, Pierre; Ghent, Chloe M; Raisch, Tobias; Sadian, Yashar; Cavadini, Simone; Sabale, Pramod M; Barford, David; Raunser, Stefan; Morgan, David O; Boland, Andreas

Yu, Jun; Raia, Pierre; Ghent, Chloe M; Raisch, Tobias; Sadian, Yashar; Cavadini, Simone; Sabale, Pramod M; Barford, David; Raunser, Stefan; Morgan, David O; Boland, Andreas.

Affiliation

Yu J; Department of Molecular Biology, University of Geneva, Geneva, Switzerland.
Raia P; Department of Molecular Biology, University of Geneva, Geneva, Switzerland.
Ghent CM; Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Raisch T; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Sadian Y; Bioimaging Center, University of Geneva, Geneva, Switzerland.
Cavadini S; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Sabale PM; Department of Organic Chemistry, NCCR Chemical Biology, University of Geneva, Geneva, Switzerland.
Barford D; MRC Laboratory of Molecular Biology, Cambridge, UK.
Raunser S; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Morgan DO; Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.
Boland A; Department of Molecular Biology, University of Geneva, Geneva, Switzerland. andreas.boland@unige.ch.

Nature ; 596(7870): 138-142, 2021 08.

Article in En | MEDLINE | ID: mdl-34290405

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CDC2 Protein Kinase / Cyclin B1 / Separase / Securin Limits: Humans Language: En Journal: Nature Year: 2021 Document type: Article Affiliation country:

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