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Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors.
Fiala, Elise M; Jayakumaran, Gowtham; Mauguen, Audrey; Kennedy, Jennifer A; Bouvier, Nancy; Kemel, Yelena; Fleischut, Megan Harlan; Maio, Anna; Salo-Mullen, Erin E; Sheehan, Margaret; Arnold, Angela G; Latham, Alicia; Carlo, Maria I; Cadoo, Karen; Murkherjee, Semanti; Slotkin, Emily K; Trippett, Tanya; Glade Bender, Julia; Meyers, Paul A; Wexler, Leonard; Dela Cruz, Filemon S; Cheung, Nai-Kong; Basu, Ellen; Kentsis, Alex; Ortiz, Michael; Francis, Jasmine H; Dunkel, Ira J; Khakoo, Yasmin; Gilheeney, Stephen; Farouk Sait, Sameer; Forlenza, Christopher J; Sulis, Maria; Karajannis, Matthias; Modak, Shakeel; Gerstle, Justin T; Heaton, Todd E; Roberts, Stephen; Yang, Ciyu; Jairam, Sowmya; Vijai, Joseph; Topka, Sabine; Friedman, Danielle N; Stadler, Zsofia K; Robson, Mark; Berger, Michael F; Schultz, Nikolaus; Ladanyi, Marc; O'Reilly, Richard J; Abramson, David H; Ceyhan-Birsoy, Ozge.
Affiliation
  • Fiala EM; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Jayakumaran G; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mauguen A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kennedy JA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bouvier N; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kemel Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Fleischut MH; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Maio A; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Salo-Mullen EE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Sheehan M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Arnold AG; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Latham A; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Carlo MI; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Cadoo K; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Murkherjee S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Slotkin EK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Trippett T; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Glade Bender J; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Meyers PA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wexler L; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Dela Cruz FS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Cheung NK; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Basu E; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kentsis A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ortiz M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Francis JH; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Dunkel IJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Khakoo Y; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gilheeney S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Farouk Sait S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Forlenza CJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Sulis M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Karajannis M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Modak S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gerstle JT; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Heaton TE; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Roberts S; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Yang C; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Jairam S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Vijai J; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Topka S; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Friedman DN; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Stadler ZK; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Robson M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Berger MF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Schultz N; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • O'Reilly RJ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Abramson DH; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ceyhan-Birsoy O; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Cancer ; 2: 357-365, 2021 03.
Article in En | MEDLINE | ID: mdl-34308366
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Germ-Line Mutation / Neoplasms Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Nat Cancer Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Germ-Line Mutation / Neoplasms Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Nat Cancer Year: 2021 Document type: Article Affiliation country: