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Targeted delivery of mPGES-1 inhibitors to macrophages via the folate receptor-ß for inflammatory pain.
Mazaleuskaya, Liudmila L; Lee, Seokwoo; Meng, Hu; Winkler, Jeffrey D; FitzGerald, Garret A.
Affiliation
  • Mazaleuskaya LL; Institute for Translational Medicine and Therapeutics, the Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: mazali@pennmedicine.upenn.edu.
  • Lee S; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: mirue7@sas.upenn.edu.
  • Meng H; Institute for Translational Medicine and Therapeutics, the Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: menghu@pennmedicine.upenn.edu.
  • Winkler JD; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: winkler@sas.upenn.edu.
  • FitzGerald GA; Institute for Translational Medicine and Therapeutics, the Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: garret@upenn.edu.
Bioorg Med Chem Lett ; 50: 128313, 2021 10 15.
Article in En | MEDLINE | ID: mdl-34390827
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Folate Receptor 2 / Prostaglandin-E Synthases / Heterocyclic Compounds, 4 or More Rings / Macrophages Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Folate Receptor 2 / Prostaglandin-E Synthases / Heterocyclic Compounds, 4 or More Rings / Macrophages Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Country of publication: