A Comparative Study of Early Mucosal Healing Following Hot Polypectomy and Cold Polypectomy.
Med Sci Monit
; 27: e933043, 2021 08 25.
Article
in En
| MEDLINE
| ID: mdl-34432770
ABSTRACT
BACKGROUND Cold polypectomy (CP) and hot polypectomy (HP) are both accepted methods for polypectomy. In recent years, the use of CP has increased for reasons of safety. However, there have been few investigations of conditions at follow-up early after resection. This prospective study from a single center aimed to compare colonic mucosal healing at 1 week following HP vs CP of benign colonic polyps <10 mm in diameter. MATERIAL AND METHODS Six patients with a total of 52 lesions under 10 mm in size were randomized to either the HP group (n=25) or CP group (n=27) using information in opaque envelopes. One week after endoscopic treatment, the site of treatment was evaluated using colonoscopy. We assessed the mean tumor size, ulcer diameter, exposed blood vessels, residual lesion, and complications. RESULTS Mean tumor size did not differ between the 2 groups (CP vs HP 5.41 mm vs 5.68 mm). The CP group had a smaller ulcer base diameter (2.70 mm vs 4.84 mm; P<0.05) and fewer exposed blood vessels than the HP group (3.7% vs 36.0%; P<0.05). One residual lesion was found in the CP group. No patients experienced delayed perforation or post-polypectomy bleeding. CONCLUSIONS Our study findings showed that at 1-week follow-up, cold polypectomy resulted in improved colonic mucosal healing, with a smaller ulcer diameter and fewer blood vessels, when compared with hot polypectomy.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
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Colonic Polyps
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Colonoscopy
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Postoperative Hemorrhage
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Endoscopic Mucosal Resection
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Mucous Membrane
Type of study:
Clinical_trials
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Observational_studies
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Prognostic_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Language:
En
Journal:
Med Sci Monit
Journal subject:
MEDICINA
Year:
2021
Document type:
Article
Affiliation country: