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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity.
Langdon, Casey G; Gadek, Katherine E; Garcia, Matthew R; Evans, Myron K; Reed, Kristin B; Bush, Madeline; Hanna, Jason A; Drummond, Catherine J; Maguire, Matthew C; Leavey, Patrick J; Finkelstein, David; Jin, Hongjian; Schreiner, Patrick A; Rehg, Jerold E; Hatley, Mark E.
Affiliation
  • Langdon CG; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Gadek KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Garcia MR; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Evans MK; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Reed KB; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Bush M; Rhodes College, Memphis, TN, 38112, USA.
  • Hanna JA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Drummond CJ; St. Jude Graduate School of Biomedical Sciences, Memphis, TN, 38105, USA.
  • Maguire MC; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Leavey PJ; Purdue Center for Cancer Research, Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
  • Finkelstein D; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Jin H; Department of Pathology, University of Otago, Dunedin, Otago, New Zealand.
  • Schreiner PA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Rehg JE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Hatley ME; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Nat Commun ; 12(1): 5520, 2021 09 17.
Article in En | MEDLINE | ID: mdl-34535684
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdomyosarcoma / PTEN Phosphohydrolase / PAX7 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdomyosarcoma / PTEN Phosphohydrolase / PAX7 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: