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The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity.
Snoznik, Carley; Medvedeva, Valentina; Mojsilovic-Petrovic, Jelena; Rudich, Paige; Oosten, James; Kalb, Robert G; Lamitina, Todd.
Affiliation
  • Snoznik C; Division of Child Neurology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15224.
  • Medvedeva V; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
  • Mojsilovic-Petrovic J; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
  • Rudich P; Division of Child Neurology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15224.
  • Oosten J; Graduate Program in Cell Biology and Molecular Physiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15261.
  • Kalb RG; Division of Child Neurology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15224.
  • Lamitina T; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611; stl52@pitt.edu robert.kalb1@northwestern.edu.
Proc Natl Acad Sci U S A ; 118(40)2021 10 05.
Article in En | MEDLINE | ID: mdl-34593637
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Nuclear Proteins / Cell Nucleus / Ubiquitin / Dipeptides / C9orf72 Protein / Ligases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Nuclear Proteins / Cell Nucleus / Ubiquitin / Dipeptides / C9orf72 Protein / Ligases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article