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Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers.
Noda, Naoto; Takagaki, Takeshi; Yodo, Yasuhide; Horibuchi, Yuzo; Iino, Shuichi; Matsuki, Shunji; Ogama, Yoichiro; Kakuyama, Hiroyoshi.
Affiliation
  • Noda N; Clinical Research, Drug Development Division, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan.
  • Takagaki T; Clinical Research, Drug Development Division, Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan.
  • Yodo Y; Data Science, Drug Development Division, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan.
  • Horibuchi Y; Oncology Clinical Development Unit, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan.
  • Iino S; Oncology Clinical Development Unit, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan.
  • Matsuki S; Fukuoka Mirai Hospital, SOUSEIKAI, Fukuoka, Japan.
  • Ogama Y; Sumida Hospital, SOUSEIKAI, Tokyo, Japan.
  • Kakuyama H; Clinical Research, Drug Development Division, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan.
Pharmacol Res Perspect ; 9(5): e00874, 2021 10.
Article in En | MEDLINE | ID: mdl-34628720
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzofurans / Naphthoquinones / Heart Conduction System / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Pharmacol Res Perspect Year: 2021 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzofurans / Naphthoquinones / Heart Conduction System / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Pharmacol Res Perspect Year: 2021 Document type: Article Affiliation country: Country of publication: