A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol.

Izumi, Yukitoshi; Cashikar, Anil G; Krishnan, Kathiresan; Paul, Steven M; Covey, Douglas F; Mennerick, Steven J; Zorumski, Charles F

Izumi, Yukitoshi; Cashikar, Anil G; Krishnan, Kathiresan; Paul, Steven M; Covey, Douglas F; Mennerick, Steven J; Zorumski, Charles F.

Affiliation

Izumi Y; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1093.
Cashikar AG; Department of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1010.
Krishnan K; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1093.
Paul SM; Department of Developmental Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110.
Covey DF; Department of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1010.
Mennerick SJ; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1093.
Zorumski CF; Department of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110-1010.

J Neurosci ; 41(49): 10054-10064, 2021 12 08.

Article in En | MEDLINE | ID: mdl-34725187

Subject(s)
Key words

lipopolysaccharide; long-term potentiation; memory; metaplasticity; neurosteroids; oxysterols

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Avoidance Learning / Microglia / Long-Term Potentiation / Hippocampus / Hydroxycholesterols Limits: Animals Language: En Journal: J Neurosci Year: 2021 Document type: Article

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