Milia-like calcinosis cutis in Down syndrome: a new case with a review of the literature.
Dermatol Online J
; 27(8)2021 Aug 15.
Article
in En
| MEDLINE
| ID: mdl-34755960
ABSTRACT
We report an 11-year-old girl who presented with white papules on the dorsal and palmar region of the hands bilaterally. The parents reported that the lesions had appeared four months before and some had resolved spontaneously. The girl was suffering from celiac disease, Down syndrome, and alopecia areata treated with topical corticosteroids. At the first visit, the girl presented with alopecia areata, corticosteroid acne, and a dozen white papules located on the hands. On dermoscopy, a whitish structureless area was seen. Histological examination showed the presence of calcium deposits without tissue damage, thus confirming the diagnosis of milia-like idiopathic calcinosis cutis. At 6-month follow up, the lesions had completely disappeared. Milia-like idiopathic calcinosis cutis is a benign cutaneous disorder consisting of calcium deposits in an apparently undamaged dermis and is typically associated with Down syndrome. Up to a quarter of patients have coexisting syringomas. The milia-like papules tend to self-resolve as patients reach adulthood, so a wait-and-see approach is recommended.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin
/
Calcinosis
/
Down Syndrome
/
Hand Dermatoses
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Dermatol Online J
Journal subject:
DERMATOLOGIA
Year:
2021
Document type:
Article