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Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection.
Snell, Laura M; Xu, Wenxi; Abd-Rabbo, Diala; Boukhaled, Giselle; Guo, Mengdi; Macleod, Bethany L; Elsaesser, Heidi J; Hezaveh, Kebria; Alsahafi, Nirmin; Lukhele, Sabelo; Nejat, Sara; Prabhakaran, Ramanandan; Epelman, Slava; McGaha, Tracy L; Brooks, David G.
Affiliation
  • Snell LM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. lausnell@iu.edu.
  • Xu W; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA. lausnell@iu.edu.
  • Abd-Rabbo D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Boukhaled G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Guo M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Macleod BL; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Elsaesser HJ; Department of Immunology, University of Toronto, Toronto, ON, Canada.
  • Hezaveh K; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Alsahafi N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Lukhele S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Nejat S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Prabhakaran R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Epelman S; Toronto General Hospital Research Institute, University Health Network (UHN), Toronto, ON, Canada.
  • McGaha TL; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Brooks DG; Department of Immunology, University of Toronto, Toronto, ON, Canada.
Nat Immunol ; 22(12): 1524-1537, 2021 12.
Article in En | MEDLINE | ID: mdl-34795443
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / Th1 Cells / B7-H1 Antigen / Immune Checkpoint Inhibitors / Lymphocytic Choriomeningitis / Lymphocytic choriomeningitis virus Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / Th1 Cells / B7-H1 Antigen / Immune Checkpoint Inhibitors / Lymphocytic Choriomeningitis / Lymphocytic choriomeningitis virus Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication: