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Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs.
Gobeil, Sophie M-C; Bobay, Benjamin G; Juvvadi, Praveen R; Cole, D Christopher; Heitman, Joseph; Steinbach, William J; Venters, Ronald A; Spicer, Leonard D.
Affiliation
  • Gobeil SM; Department of Biochemistry, Duke Universitygrid.26009.3d, Durham, North Carolina, USA.
  • Bobay BG; Department of Radiology, Duke Universitygrid.26009.3d, Durham, North Carolina, USA.
  • Juvvadi PR; Duke University NMR Center, Duke University Medical Center, Durham, North Carolina, USA.
  • Cole DC; Division of Pediatric Infectious Diseases, Department of Pediatrics, Duke Universitygrid.26009.3d Medical Center, Durham, North Carolina, USA.
  • Heitman J; Division of Pediatric Infectious Diseases, Department of Pediatrics, Duke Universitygrid.26009.3d Medical Center, Durham, North Carolina, USA.
  • Steinbach WJ; Department of Molecular Genetics and Microbiology, Duke Universitygrid.26009.3d Medical Center, Durham, North Carolina, USA.
  • Venters RA; Division of Pediatric Infectious Diseases, Department of Pediatrics, Duke Universitygrid.26009.3d Medical Center, Durham, North Carolina, USA.
  • Spicer LD; Department of Molecular Genetics and Microbiology, Duke Universitygrid.26009.3d Medical Center, Durham, North Carolina, USA.
mBio ; 12(6): e0300021, 2021 12 21.
Article in En | MEDLINE | ID: mdl-34809463
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Tacrolimus / Calcineurin / Calcineurin Inhibitors / Mucor / Mucormycosis / Antifungal Agents Limits: Humans Language: En Journal: MBio Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Tacrolimus / Calcineurin / Calcineurin Inhibitors / Mucor / Mucormycosis / Antifungal Agents Limits: Humans Language: En Journal: MBio Year: 2021 Document type: Article Affiliation country: Country of publication: