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Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.
Ojha, Ritu; Chen, I-Chung; Hsieh, Chien-Ming; Nepali, Kunal; Lai, Row-Wen; Hsu, Kai-Cheng; Lin, Tony Eight; Pan, Shiow-Lin; Chen, Mei-Chuan; Liou, Jing-Ping.
Affiliation
  • Ojha R; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
  • Chen IC; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
  • Hsieh CM; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
  • Nepali K; TMU Research Center of Drug Discovery, Taipei Medical University, Taipei 110031, Taiwan.
  • Lai RW; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
  • Hsu KC; TMU Research Center of Drug Discovery, Taipei Medical University, Taipei 110031, Taiwan.
  • Lin TE; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
  • Pan SL; Graduate Institute of Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110031, Taiwan.
  • Chen MC; TMU Research Center of Drug Discovery, Taipei Medical University, Taipei 110031, Taiwan.
  • Liou JP; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei 110031, Taiwan.
J Med Chem ; 64(24): 17824-17845, 2021 12 23.
Article in En | MEDLINE | ID: mdl-34908406
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pargyline / Prostatic Neoplasms / Histone Demethylases / Histone Deacetylase Inhibitors / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pargyline / Prostatic Neoplasms / Histone Demethylases / Histone Deacetylase Inhibitors / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication: