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Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae.
Berry, Sophia K; Rust, Steven; Caceres, Carolina; Irving, Lorraine; Bartholdson Scott, Josefin; Tabor, David E; Dougan, Gordon; Christie, Graham; Warrener, Paul; Minter, Ralph; Grant, Andrew J.
Affiliation
  • Berry SK; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
  • Rust S; Antibody Discovery and Protein Engineering, Biopharmaceuticals R&d, AstraZeneca, Cambridge, UK.
  • Caceres C; Antibody Discovery and Protein Engineering, Biopharmaceuticals R&d, AstraZeneca, Cambridge, UK.
  • Irving L; Microbial Sciences, Biopharmaceuticals R&d, AstraZeneca, Gaithersburg, MD, USA.
  • Bartholdson Scott J; Antibody Discovery and Protein Engineering, Biopharmaceuticals R&d, AstraZeneca, Cambridge, UK.
  • Tabor DE; Cambridge Institute for Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Dougan G; Microbial Sciences, Biopharmaceuticals R&d, AstraZeneca, Gaithersburg, MD, USA.
  • Christie G; Cambridge Institute for Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Warrener P; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.
  • Minter R; Microbial Sciences, Biopharmaceuticals R&d, AstraZeneca, Gaithersburg, MD, USA.
  • Grant AJ; Antibody Discovery and Protein Engineering, Biopharmaceuticals R&d, AstraZeneca, Cambridge, UK.
MAbs ; 14(1): 2006123, 2022.
Article in En | MEDLINE | ID: mdl-34923908
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Klebsiella Infections / Lipopolysaccharides / Klebsiella pneumoniae / Macrophages / Antibodies, Bacterial / Epitopes Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Klebsiella Infections / Lipopolysaccharides / Klebsiella pneumoniae / Macrophages / Antibodies, Bacterial / Epitopes Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Document type: Article Affiliation country: