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Indoxyl Sulfate Contributes to mTORC1-Induced Renal Fibrosis via The OAT/NADPH Oxidase/ROS Pathway.
Nakano, Takehiro; Watanabe, Hiroshi; Imafuku, Tadashi; Tokumaru, Kai; Fujita, Issei; Arimura, Nanaka; Maeda, Hitoshi; Tanaka, Motoko; Matsushita, Kazutaka; Fukagawa, Masafumi; Maruyama, Toru.
Affiliation
  • Nakano T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Watanabe H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Imafuku T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Tokumaru K; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Fujita I; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Arimura N; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Maeda H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
  • Tanaka M; Department of Nephrology, Akebono Clinic, Kumamoto 8614112, Japan.
  • Matsushita K; Department of Nephrology, Akebono Clinic, Kumamoto 8614112, Japan.
  • Fukagawa M; Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Kanagawa 2591193, Japan.
  • Maruyama T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 8620973, Japan.
Toxins (Basel) ; 13(12)2021 12 18.
Article in En | MEDLINE | ID: mdl-34941746
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine-Oxo-Acid Transaminase / Fibrosis / NADPH Oxidases / Mechanistic Target of Rapamycin Complex 1 / Indican / Kidney Diseases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Toxins (Basel) Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine-Oxo-Acid Transaminase / Fibrosis / NADPH Oxidases / Mechanistic Target of Rapamycin Complex 1 / Indican / Kidney Diseases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Toxins (Basel) Year: 2021 Document type: Article Affiliation country: Country of publication: