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The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.
Krastev, Dragomir B; Li, Shudong; Sun, Yilun; Wicks, Andrew J; Hoslett, Gwendoline; Weekes, Daniel; Badder, Luned M; Knight, Eleanor G; Marlow, Rebecca; Pardo, Mercedes Calvo; Yu, Lu; Talele, Tanaji T; Bartek, Jiri; Choudhary, Jyoti S; Pommier, Yves; Pettitt, Stephen J; Tutt, Andrew N J; Ramadan, Kristijan; Lord, Christopher J.
Affiliation
  • Krastev DB; The CRUK Gene Function Laboratory, London, UK.
  • Li S; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Sun Y; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Wicks AJ; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Hoslett G; The CRUK Gene Function Laboratory, London, UK.
  • Weekes D; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Badder LM; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
  • Knight EG; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Marlow R; The Breast Cancer Now Research Unit, King's College London, London, UK.
  • Pardo MC; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Yu L; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
  • Talele TT; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.
  • Bartek J; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.
  • Choudhary JS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
  • Pommier Y; Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Pettitt SJ; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden.
  • Tutt ANJ; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.
  • Ramadan K; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Lord CJ; The CRUK Gene Function Laboratory, London, UK. Stephen.Pettitt@icr.ac.uk.
Nat Cell Biol ; 24(1): 62-73, 2022 01.
Article in En | MEDLINE | ID: mdl-35013556
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Poly(ADP-ribose) Polymerase Inhibitors / Poly (ADP-Ribose) Polymerase-1 / Valosin Containing Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Cell Biol Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Poly(ADP-ribose) Polymerase Inhibitors / Poly (ADP-Ribose) Polymerase-1 / Valosin Containing Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Cell Biol Year: 2022 Document type: Article Affiliation country: Country of publication: