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Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma.
Serratì, Simona; Guida, Michele; Di Fonte, Roberta; De Summa, Simona; Strippoli, Sabino; Iacobazzi, Rosa Maria; Quarta, Alessandra; De Risi, Ivana; Guida, Gabriella; Paradiso, Angelo; Porcelli, Letizia; Azzariti, Amalia.
Affiliation
  • Serratì S; Laboratory of Nanotechnology, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Guida M; Rare Tumors and Melanoma Unit, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Di Fonte R; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • De Summa S; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Strippoli S; Rare Tumors and Melanoma Unit, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Iacobazzi RM; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Quarta A; CNR NANOTEC-Istituto di Nanotecnologia, National Research Council (CNR), via Monteroni, 73100, Lecce, Italy.
  • De Risi I; Rare Tumors and Melanoma Unit, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Guida G; Department of Basic Medical Sciences Neurosciences and Sense Organs, University of Bari, Piazza G. Cesare, 11, 70124, Bari, Italy.
  • Paradiso A; Scientific Directorate, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Porcelli L; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy.
  • Azzariti A; Laboratory of Nanotechnology, IRCCS Istituto Tumori Giovanni Paolo II, V.le O. Flacco, 65, 70124, Bari, Italy. a.azzariti@oncologico.bari.it.
Mol Cancer ; 21(1): 20, 2022 01 18.
Article in En | MEDLINE | ID: mdl-35042524
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Drug Resistance, Neoplasm / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Extracellular Vesicles / Melanoma Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Drug Resistance, Neoplasm / B7-H1 Antigen / Programmed Cell Death 1 Receptor / Extracellular Vesicles / Melanoma Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: