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N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
Pan, Ruangang; Kindler, Eveline; Cao, Liu; Zhou, Yu; Zhang, Zhen; Liu, Qianyun; Ebert, Nadine; Züst, Roland; Sun, Ying; Gorbalenya, Alexander E; Perlman, Stanley; Thiel, Volker; Chen, Yu; Guo, Deyin.
Affiliation
  • Pan R; State Key Laboratory of Virology, Modern Virology Research Center, Institute for Vaccine Research and RNA Institute, College of Life Sciences, Wuhan Universitygrid.49470.3e, Wuhan, People's Republic of China.
  • Kindler E; Institute for Virology and Immunology IVI, Mittelhäusern, Switzerland.
  • Cao L; Department of Infectious Diseases and Pathobiology, Vetsuisse Facility, University of Bern, Bern, Switzerland.
  • Zhou Y; State Key Laboratory of Virology, Modern Virology Research Center, Institute for Vaccine Research and RNA Institute, College of Life Sciences, Wuhan Universitygrid.49470.3e, Wuhan, People's Republic of China.
  • Zhang Z; School of Medicine, Sun Yat-sen University, Guangzhou, People's Republic of China.
  • Liu Q; School of Mathematics and Statistics, Wuhan Universitygrid.49470.3e, Wuhan, China.
  • Ebert N; State Key Laboratory of Virology, Modern Virology Research Center, Institute for Vaccine Research and RNA Institute, College of Life Sciences, Wuhan Universitygrid.49470.3e, Wuhan, People's Republic of China.
  • Züst R; State Key Laboratory of Virology, Modern Virology Research Center, Institute for Vaccine Research and RNA Institute, College of Life Sciences, Wuhan Universitygrid.49470.3e, Wuhan, People's Republic of China.
  • Sun Y; Institute for Virology and Immunology IVI, Mittelhäusern, Switzerland.
  • Gorbalenya AE; Department of Infectious Diseases and Pathobiology, Vetsuisse Facility, University of Bern, Bern, Switzerland.
  • Perlman S; Spiez Laboratory, Federal Office for Civil Protection, Spiez, Switzerland.
  • Thiel V; State Key Laboratory of Virology, Modern Virology Research Center, Institute for Vaccine Research and RNA Institute, College of Life Sciences, Wuhan Universitygrid.49470.3e, Wuhan, People's Republic of China.
  • Chen Y; Department of Medical Microbiology, Leiden University Medical Centergrid.10419.3d, Leiden, The Netherlands.
  • Guo D; Faculty of Bioengineering & Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
mBio ; 13(1): e0366221, 2022 02 22.
Article in En | MEDLINE | ID: mdl-35073761
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Murine hepatitis virus / COVID-19 Limits: Animals / Humans Language: En Journal: MBio Year: 2022 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Murine hepatitis virus / COVID-19 Limits: Animals / Humans Language: En Journal: MBio Year: 2022 Document type: Article Country of publication: