The Effects of Environmental Contaminant Exposure on Reproductive Aging and the Menopause Transition.
Curr Environ Health Rep
; 9(1): 53-79, 2022 03.
Article
in En
| MEDLINE
| ID: mdl-35103957
ABSTRACT
PURPOSE OF REVIEW Menopause marks the end of a woman's reproductive lifetime. On average, natural menopause occurs at 51 years of age. However, some women report an earlier age of menopause than the national average. This can be problematic for women who delay starting a family. Moreover, early onset of menopause is associated with increased risk of cardiovascular disease, depression, osteoporosis, and premature death. This review investigates associations between exposure to endocrine-disrupting chemicals (EDCs) and earlier onset of menopause. RECENT FINDINGS:
Recent data suggest exposure to certain EDCs may accelerate reproductive aging and contribute to earlier onset of menopause. Human and rodent-based studies identify positive associations between exposure to certain EDCs/environmental contaminants and reproductive aging, earlier onset of menopause, and occurrence of vasomotor symptoms. These findings increase our understanding of the detrimental effects of EDCs on female reproduction and will help lead to the development of strategies for the treatment/prevention of EDC-induced reproductive aging.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Reproduction
/
Endocrine Disruptors
Type of study:
Prognostic_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Curr Environ Health Rep
Year:
2022
Document type:
Article
Affiliation country: