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Venous Thromboembolic Events in Adolescent and Young Adult Patients with Acute Lymphoblastic Leukemia.
Jones, Sandra R; Patel, Roshni B; Rahim, Mahvish Q; Althouse, Sandra K; Batra, Sandeep.
Affiliation
  • Jones SR; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Patel RB; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
  • Rahim MQ; Department of Pediatrics, Riley Hospital for Children, Indianapolis, Indiana, USA.
  • Althouse SK; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, SA.
  • Batra S; Department of Pediatrics, Riley Hospital for Children, Indianapolis, Indiana, USA.
J Adolesc Young Adult Oncol ; 11(6): 600-604, 2022 12.
Article in En | MEDLINE | ID: mdl-35108120
ABSTRACT
Acute venous thromboembolisms (VTEs) are serious complications that occur during acute lymphoblastic leukemia (ALL) chemotherapy. The data elucidating risk factors for developing VTEs are limited in adolescent and young adult patients being treated per pediatric ALL protocols. In a cohort of 66 patients, 14 (21%) experienced VTEs. The majority of VTEs occurred during induction chemotherapy after the first dose of asparaginase, and in the upper extremities. Five-year relapse-free and overall survival were not impacted by VTEs. Contrary to VTEs in adults, hypoalbuminemia and increased body mass index were not associated with an elevated risk of VTE.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Adolescent / Adult / Child / Humans Language: En Journal: J Adolesc Young Adult Oncol Year: 2022 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Adolescent / Adult / Child / Humans Language: En Journal: J Adolesc Young Adult Oncol Year: 2022 Document type: Article Affiliation country: