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Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.
Gershenson, David M; Miller, Austin; Brady, William E; Paul, James; Carty, Karen; Rodgers, William; Millan, David; Coleman, Robert L; Moore, Kathleen N; Banerjee, Susana; Connolly, Kate; Secord, Angeles Alvarez; O'Malley, David M; Dorigo, Oliver; Gaillard, Stephanie; Gabra, Hani; Slomovitz, Brian; Hanjani, Parviz; Farley, John; Churchman, Michael; Ewing, Ailith; Hollis, Robert L; Herrington, C Simon; Huang, Helen Q; Wenzel, Lari; Gourley, Charlie.
Affiliation
  • Gershenson DM; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: dgershen@mdanderson.org.
  • Miller A; NRG Oncology, Clinical Trial Development Division, Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Brady WE; NRG Oncology, Clinical Trial Development Division, Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Paul J; Cancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Carty K; Cancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Rodgers W; New York Presbyterian/Queens, Department of Pathology, Weill Medical College of Cornell University, Flushing, NY, USA.
  • Millan D; Queen Elizabeth University Hospital, Glasgow, UK.
  • Coleman RL; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Moore KN; Stephenson Cancer Center at the University of Oklahoma, Oklahoma City, OK, USA.
  • Banerjee S; The Royal Marsden Hospital NHS Foundation Trust, The Institute of Cancer Research, London, UK.
  • Connolly K; Edinburgh Cancer Centre, Edinburgh, UK.
  • Secord AA; Duke Cancer Institute, Durham, NC, USA.
  • O'Malley DM; The Ohio State University and the James Cancer Center, Columbus, OH, USA.
  • Dorigo O; Stanford Cancer Institute, Stanford University, Stanford, CA, USA.
  • Gaillard S; Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD, USA.
  • Gabra H; Surgery and Cancer, Imperial College London, London, UK.
  • Slomovitz B; Division ofGynecologic Oncology, Mount Sinai Medical Center, Miami Beach, FL, USA.
  • Hanjani P; Abington Memorial Hospital, Abington, PA, USA.
  • Farley J; St Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
  • Churchman M; Nicola Murray Centre for Ovarian Cancer Research, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK.
  • Ewing A; MRC Human Genetics Unit and CRUK Edinburgh Centre, MRC Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Hollis RL; Nicola Murray Centre for Ovarian Cancer Research, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK.
  • Herrington CS; Nicola Murray Centre for Ovarian Cancer Research, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK.
  • Huang HQ; NRG Oncology, Clinical Trial Development Division, Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Wenzel L; Medicine and Public Health, University of California at Irvine, Irvine, CA, USA.
  • Gourley C; Nicola Murray Centre for Ovarian Cancer Research, Institute of Genetics and Cancer, Western General Hospital, Edinburgh, UK.
Lancet ; 399(10324): 541-553, 2022 02 05.
Article in En | MEDLINE | ID: mdl-35123694
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Pyridones / Pyrimidinones / Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Ovarian Epithelial Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Middle aged Country/Region as subject: America do norte / Europa Language: En Journal: Lancet Year: 2022 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Pyridones / Pyrimidinones / Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Ovarian Epithelial Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Middle aged Country/Region as subject: America do norte / Europa Language: En Journal: Lancet Year: 2022 Document type: Article Country of publication: