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Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Kuzuya, Maki; Hirano, Hidemi; Hayashida, Kenichi; Watanabe, Masakatsu; Kobayashi, Kazumi; Terada, Tohru; Mahmood, Md Iqbal; Tama, Florence; Tani, Kazutoshi; Fujiyoshi, Yoshinori; Oshima, Atsunori.
Affiliation
  • Kuzuya M; Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Hirano H; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Hayashida K; Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Watanabe M; Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Kobayashi K; JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-8558, Japan.
  • Terada T; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
  • Mahmood MI; Department of Physics, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Tama F; Department of Physics, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Tani K; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
  • Fujiyoshi Y; RIKEN Center for Computational Science, Kobe, Hyogo 650-0047, Japan.
  • Oshima A; Graduate School of Medicine, Mie University, 2-174 Edobashi Tsu, Mie 514-8507, Japan.
Sci Signal ; 15(720): eabg6941, 2022 02 08.
Article in En | MEDLINE | ID: mdl-35133866
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Connexins Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2022 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Connexins Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2022 Document type: Article Affiliation country: