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Droplet-based screening of phosphate transfer catalysis reveals how epistasis shapes MAP kinase interactions with substrates.
Scheele, Remkes A; Lindenburg, Laurens H; Petek, Maya; Schober, Markus; Dalby, Kevin N; Hollfelder, Florian.
Affiliation
  • Scheele RA; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.
  • Lindenburg LH; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.
  • Petek M; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.
  • Schober M; Faculty of Medicine, University of Maribor, SI-2000, Maribor, Slovenia.
  • Dalby KN; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.
  • Hollfelder F; Division of Chemical Biology and Medicinal Chemistry, The University of Texas at Austin, Austin, TX, 78712, USA.
Nat Commun ; 13(1): 844, 2022 02 11.
Article in En | MEDLINE | ID: mdl-35149678

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphates / Mitogen-Activated Protein Kinases / Epistasis, Genetic Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphates / Mitogen-Activated Protein Kinases / Epistasis, Genetic Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: