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Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.
Zhang, Mao-Feng; Luo, Xiao-Yu; Zhang, Cheng; Wang, Chao; Wu, Xi-Shan; Xiang, Qiu-Ping; Xu, Yong; Zhang, Yan.
Affiliation
  • Zhang MF; College of Pharmacy, Taizhou Polytechnic College, Taizhou, 225300, China. zhang_maofeng@163.com.
  • Luo XY; Guangzhou Younan Technology Co., Ltd, Guangzhou, 510663, China.
  • Zhang C; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China.
  • Wang C; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China.
  • Wu XS; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Xiang QP; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China.
  • Xu Y; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China.
  • Zhang Y; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China. xu_yong@gibh.ac.cn.
Acta Pharmacol Sin ; 43(10): 2735-2748, 2022 Oct.
Article in En | MEDLINE | ID: mdl-35264812
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: