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H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth.
Lu, Chunwan; Yang, Dafeng; Klement, John D; Colson, Yolonda L; Oberlies, Nicholas H; Pearce, Cedric J; Colby, Aaron H; Grinstaff, Mark W; Liu, Zhuoqi; Shi, Huidong; Ding, Han-Fei; Liu, Kebin.
Affiliation
  • Lu C; School of Life Sciences, Tianjin University, Tianjin, 300072, China. Chunwanlu@tju.edu.cn.
  • Yang D; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA, 30912, USA. Chunwanlu@tju.edu.cn.
  • Klement JD; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA, 30912, USA.
  • Colson YL; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.
  • Oberlies NH; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
  • Pearce CJ; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA, 30912, USA.
  • Colby AH; Georgia Cancer Center, Medical College of Georgia, Augusta, GA, 30912, USA.
  • Grinstaff MW; Charlie Norwood VA Medical Center, Augusta, GA, 30904, USA.
  • Liu Z; Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
  • Shi H; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC, 27402, USA.
  • Ding HF; Mycosynthetix, Inc, Hillsborough, NC, 27278, USA.
  • Liu K; Ionic Pharmaceuticals, Brookline, MA, 02445, USA.
Oncogene ; 41(18): 2651-2662, 2022 04.
Article in En | MEDLINE | ID: mdl-35351997
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma / Mesothelioma Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma / Mesothelioma Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2022 Document type: Article Affiliation country: