Sleep Apnea Screening in Children With Sickle Cell Anemia.
J Pediatr Hematol Oncol
; 44(7): 354-357, 2022 10 01.
Article
in En
| MEDLINE
| ID: mdl-35383664
ABSTRACT
BACKGROUND:
Screening for obstructive sleep apnea (OSA) is recommended by current guidelines in children with sickle cell anemia (SCA), but no specific approach is described. The Pediatric Sleep Questionnaire (PSQ) is a validated detection tool for OSA in children. We assessed the utility of PSQ to screen for OSA in children with concomitant SCA and snoring. MATERIALS ANDMETHODS:
A prospective study, in children 4 to 18 years old with SCA. Subjects were assessed for snoring and PSQ administered at the same visit. All children with snoring were then referred for polysomnography.RESULTS:
A total of 106 subjects were screened. Habitual snoring prevalence was 51/106 (48.1%). In the snoring group, OSA was detected in 83.9% (apnea-hypopnea index [AHI] ≥1.0/h) and 22.6% (AHI ≥5.0/h), respectively. Sensitivity and specificity of PSQ in children with snoring was 46.2% and 20.0% (AHI ≥1.0/h), and 57.1% and 50.0% (AHI ≥5.0/h), respectively. Physician assessment for snoring had a high sensitivity of 70.3% but low specificity of 58.4% (AHI ≥1.0/h), and 87.5% and 41.5% (AHI ≥5.0/h), respectively.CONCLUSION:
PSQ is a poor screening tool for detection of OSA in those children with SCA who snore. Physician assessment for snoring could however be an initial approach before polysomnography.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sleep Apnea Syndromes
/
Sleep Apnea, Obstructive
/
Anemia, Sickle Cell
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
J Pediatr Hematol Oncol
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Year:
2022
Document type:
Article