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The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research.
Muhl, Lars; He, Liqun; Sun, Ying; Andaloussi Mäe, Maarja; Pietilä, Riikka; Liu, Jianping; Genové, Guillem; Zhang, Lei; Xie, Yuan; Leptidis, Stefanos; Mocci, Giuseppe; Stritt, Simon; Osman, Ahmed; Anisimov, Andrey; Hemanthakumar, Karthik Amudhala; Räsänen, Markus; Hansson, Emil M; Björkegren, Johan; Vanlandewijck, Michael; Blomgren, Klas; Mäkinen, Taija; Peng, Xiao-Rong; Hu, Yizhou; Ernfors, Patrik; Arnold, Thomas D; Alitalo, Kari; Lendahl, Urban; Betsholtz, Christer.
Affiliation
  • Muhl L; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • He L; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Key Laboratory of Post-Neuro-injury Neuro-Repair and Regeneration in Central Nervous Sy
  • Sun Y; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Andaloussi Mäe M; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Pietilä R; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Liu J; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • Genové G; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • Zhang L; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an China.
  • Xie Y; Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an China.
  • Leptidis S; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • Mocci G; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • Stritt S; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Osman A; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
  • Anisimov A; Wihuri Research Institute and Translational Cancer Medicine Program, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
  • Hemanthakumar KA; Wihuri Research Institute and Translational Cancer Medicine Program, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
  • Räsänen M; Wihuri Research Institute and Translational Cancer Medicine Program, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
  • Hansson EM; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden.
  • Björkegren J; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden; Institute of Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Vanlandewijck M; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Blomgren K; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden; Department of Pediatric Oncology, Karolinska University Hospital, Stockholm Sweden.
  • Mäkinen T; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
  • Peng XR; Cardiovascular, Renal and Metabolism, AstraZeneca BioPharmaceutical R&D, Gothenburg, Sweden.
  • Hu Y; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
  • Ernfors P; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
  • Arnold TD; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA.
  • Alitalo K; Wihuri Research Institute and Translational Cancer Medicine Program, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.
  • Lendahl U; Department of Cell and Molecular Biology, Karolinska Institutet, Solna, Sweden. Electronic address: urban.lendahl@ki.se.
  • Betsholtz C; Department of Medicine, Huddinge, Karolinska Institutet, Solna, Sweden; Department of Immunology, Genetics, and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden. Electronic address: christer.betsholtz@igp.uu.se.
Stem Cell Reports ; 17(5): 1089-1104, 2022 05 10.
Article in En | MEDLINE | ID: mdl-35452595
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pericytes / Angiotensin-Converting Enzyme 2 / COVID-19 Limits: Animals Language: En Journal: Stem Cell Reports Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pericytes / Angiotensin-Converting Enzyme 2 / COVID-19 Limits: Animals Language: En Journal: Stem Cell Reports Year: 2022 Document type: Article Affiliation country: Country of publication: