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Rituximab as Second-Line Treatment in Anti-NMDAR Encephalitis after Herpes Simplex Encephalitis in Children.
Carrascosa-García, Paula; Oviedo-Melgares, Lidia; Torres-Fernández, David; Blázquez-Gamero, Daniel; Armangué, Thaís; Vila-Bedmar, Sara; Prieto-Tato, Luis; Miranda-Herrero, Concepción; Santos-Sebastián, Mar; Rincón-López, Elena María; Fernández-Cooke, Elisa.
Affiliation
  • Carrascosa-García P; Department of Pediatrics, Pediatric Infectious Diseases Unit, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), RITIP, Madrid, Spain.
  • Oviedo-Melgares L; Department of Pediatrics, Pediatric Intensive Care Unit, Hospital Universitario, 12 de Octubre, Madrid, Spain.
  • Torres-Fernández D; Department of Pediatrics, Pediatric Infectious Diseases Unit, Instituto de Investigación Hospital 12 de Octubre (Imas12), Hospital Universitario, 12 de Octubre, Avda Córdoba s/n. 28041, RITIP, Madrid, Spain.
  • Blázquez-Gamero D; Department of Pediatrics, Pediatric Infectious Diseases Unit, Instituto de Investigación Hospital 12 de Octubre (Imas12), Hospital Universitario, 12 de Octubre, Avda Córdoba s/n. 28041, RITIP, Madrid, Spain.
  • Armangué T; Pediatric Neuroimmunology Unit, Neuroimmunology Program, Institutd' Investigacions Biomèdiques IDIBAPS-Hospital Clinic, Neurology Service, Sant Joan de Deu Children's Hospital, University of Barcelona, Barcelona, Spain.
  • Vila-Bedmar S; Department of Pediatrics, Pediatric Neurology Unit, Hospital Universitario, 12 de Octubre, Madrid, Spain.
  • Prieto-Tato L; Department of Pediatrics, Pediatric Infectious Diseases Unit, Instituto de Investigación Hospital 12 de Octubre (Imas12), Hospital Universitario, 12 de Octubre, Avda Córdoba s/n. 28041, RITIP, Madrid, Spain. luismanuel.prieto@salud.madrid.org.
  • Miranda-Herrero C; Department of Neuropediatrics, Hospital Materno Infantil Gregorio Marañón, Madrid, Spain.
  • Santos-Sebastián M; Department of Pediatrics, Pediatric Infectious Diseases Unit, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), RITIP, Madrid, Spain.
  • Rincón-López EM; Department of Pediatrics, Pediatric Infectious Diseases Unit, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), RITIP, Madrid, Spain.
  • Fernández-Cooke E; Department of Pediatrics, Pediatric Infectious Diseases Unit, Instituto de Investigación Hospital 12 de Octubre (Imas12), Hospital Universitario, 12 de Octubre, Avda Córdoba s/n. 28041, RITIP, Madrid, Spain.
Indian J Pediatr ; 89(10): 1031-1033, 2022 10.
Article in En | MEDLINE | ID: mdl-35467320
ABSTRACT
The long-term response of two infants with anti-N-methyl-D-aspartate receptor (anti-NMDAR) post herpes simplex encephalitis treated with rituximab is reported here. Rituximab may improve the course of the disease and should be considered early as second-line treatment. Data on the long-term effect of rituximab in B cell depletion and immunoglobulins levels in infants are needed.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Encephalitis, Herpes Simplex / Anti-N-Methyl-D-Aspartate Receptor Encephalitis Type of study: Diagnostic_studies Limits: Humans / Infant Language: En Journal: Indian J Pediatr Year: 2022 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Encephalitis, Herpes Simplex / Anti-N-Methyl-D-Aspartate Receptor Encephalitis Type of study: Diagnostic_studies Limits: Humans / Infant Language: En Journal: Indian J Pediatr Year: 2022 Document type: Article Affiliation country: