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Asn25 Deamidation as an Allosteric Tool to Increase IFNß-1a Biological Activity.
Lipari, Elisa; Saporiti, Simona; Eberini, Ivano; Massimo, Luigia; Mazzarella, Enrico; Anderloni, Giulia; Rossi, Mara; D'Amici, Fabio; Pergola, Carlo; Palinsky, Wolf; D'Acunto, Cosimo Walter; Centola, Fabio.
Affiliation
  • Lipari E; Analytical Development Biotech, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
  • Saporiti S; Dipartimento di Scienze Farmacologiche e Biomolecolari and Università degli Studi di Milano, Milano, Italy.
  • Eberini I; Dipartimento di Scienze Farmacologiche e Biomolecolari and Università degli Studi di Milano, Milano, Italy.
  • Massimo L; Data Science Research Center (DSRC), Università degli Studi di Milano, Milano, Italy.
  • Mazzarella E; Analytical Development Biotech, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
  • Anderloni G; Dipartimento di Farmacia, Università degli Studi di Salerno, Fisciano, Italy.
  • Rossi M; Analytical Development Biotech, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
  • D'Amici F; Sezione di Medicina Interna e Malattie Metaboliche, Dipartimento di Medicina Interna e Specialistica, DIBIMIS, Università di Palermo, Palermo, Italy.
  • Pergola C; Analytical Development Biotech, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
  • Palinsky W; Sezione di Medicina Interna e Malattie Metaboliche, Dipartimento di Medicina Interna e Specialistica, DIBIMIS, Università di Palermo, Palermo, Italy.
  • D'Acunto CW; Global Analytical Pharmaceutical Science and Innovation, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
  • Centola F; Analytical Development Biotech, Merck Serono S.p.A., Rome, Italy (an Affiliate of Merck KGaA, Darmstadt, Germany).
J Interferon Cytokine Res ; 42(6): 251-266, 2022 06.
Article in En | MEDLINE | ID: mdl-35527626
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Interferon-beta Language: En Journal: J Interferon Cytokine Res Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Interferon-beta Language: En Journal: J Interferon Cytokine Res Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Document type: Article Country of publication: