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Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.
Howe, Laurence J; Nivard, Michel G; Morris, Tim T; Hansen, Ailin F; Rasheed, Humaira; Cho, Yoonsu; Chittoor, Geetha; Ahlskog, Rafael; Lind, Penelope A; Palviainen, Teemu; van der Zee, Matthijs D; Cheesman, Rosa; Mangino, Massimo; Wang, Yunzhang; Li, Shuai; Klaric, Lucija; Ratliff, Scott M; Bielak, Lawrence F; Nygaard, Marianne; Giannelis, Alexandros; Willoughby, Emily A; Reynolds, Chandra A; Balbona, Jared V; Andreassen, Ole A; Ask, Helga; Baras, Aris; Bauer, Christopher R; Boomsma, Dorret I; Campbell, Archie; Campbell, Harry; Chen, Zhengming; Christofidou, Paraskevi; Corfield, Elizabeth; Dahm, Christina C; Dokuru, Deepika R; Evans, Luke M; de Geus, Eco J C; Giddaluru, Sudheer; Gordon, Scott D; Harden, K Paige; Hill, W David; Hughes, Amanda; Kerr, Shona M; Kim, Yongkang; Kweon, Hyeokmoon; Latvala, Antti; Lawlor, Deborah A; Li, Liming; Lin, Kuang; Magnus, Per.
Affiliation
  • Howe LJ; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK. laurence.howe@bristol.ac.uk.
  • Nivard MG; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. laurence.howe@bristol.ac.uk.
  • Morris TT; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.
  • Hansen AF; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Rasheed H; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Cho Y; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
  • Chittoor G; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Ahlskog R; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
  • Lind PA; Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Palviainen T; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • van der Zee MD; Department of Population Health Sciences, Geisinger Health, Danville, PA, USA.
  • Cheesman R; Department of Government, Uppsala University, Uppsala, Sweden.
  • Mangino M; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Wang Y; School of Biomedical Sciences, Queensland University of Technology, Brisbane, Australia.
  • Li S; Faculty of Medicine, University of Queensland, Brisbane, Australia.
  • Klaric L; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
  • Ratliff SM; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.
  • Bielak LF; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
  • Nygaard M; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
  • Giannelis A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Willoughby EA; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK.
  • Reynolds CA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Balbona JV; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.
  • Andreassen OA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Ask H; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
  • Baras A; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Bauer CR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Boomsma DI; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Campbell A; The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.
  • Campbell H; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
  • Chen Z; Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
  • Christofidou P; Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
  • Corfield E; Department of Psychology, University of California, Riverside, Riverside, CA, USA.
  • Dahm CC; Department of Psychology & Neuroscience, University of Colorado at Boulder, Boulder, CO, USA.
  • Dokuru DR; Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO, USA.
  • Evans LM; NORMENT Centre, University of Oslo, Oslo, Norway.
  • de Geus EJC; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
  • Giddaluru S; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.
  • Gordon SD; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Harden KP; BioMarin Pharmaceutical Inc., Novato, CA, USA.
  • Hill WD; Biomedical and Translational Informatics, Geisinger Health, Danville, PA, USA.
  • Hughes A; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.
  • Kerr SM; Amsterdam Public Health (APH) and Amsterdam Reproduction and Development (AR&D), Amsterdam, the Netherlands.
  • Kim Y; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Kweon H; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
  • Latvala A; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Lawlor DA; MRC Population Health Research Unit, University of Oxford, Oxford, UK.
  • Li L; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Lin K; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.
  • Magnus P; Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.
Nat Genet ; 54(5): 581-592, 2022 05.
Article in En | MEDLINE | ID: mdl-35534559
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Genome-Wide Association Study Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Genome-Wide Association Study Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: Country of publication: