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Antibody Seronegativity in COVID-19 RT-PCR-Positive Children.
Bhatt, Maala; Zemek, Roger L; Tang, Ken; Malley, Richard; Plint, Amy C; Pham-Huy, Anne; Dawson, Jennifer; McGahern, Candice; Pelchat, Martin; Arnold, Corey; Galipeau, Yannick; Langlois, Marc-André.
Affiliation
  • Bhatt M; From the Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
  • Zemek RL; From the Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
  • Tang K; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
  • Malley R; Division of Infectious Diseases, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Plint AC; From the Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
  • Pham-Huy A; From the Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
  • Dawson J; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
  • McGahern C; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
  • Pelchat M; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Arnold C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Galipeau Y; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Langlois MA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Pediatr Infect Dis J ; 41(8): e318-e320, 2022 08 01.
Article in En | MEDLINE | ID: mdl-35544731
ABSTRACT
This substudy of a prospective case-ascertained household transmission study investigated severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction-positive individuals without antibody development and factors associated with nonseroconversion. Approximately 1 of 8 individuals with coronavirus disease 2019 did not seroconvert. Children, particularly the youngest, were approximately half as likely to seroconvert compared with adults. Apart from the absence of fever/chills, individual symptoms did not strongly predict nonseroconversion.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Child / Humans Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2022 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Child / Humans Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2022 Document type: Article Affiliation country: