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First-in-man, first-in-class phase I study with the monopolar spindle 1 kinase inhibitor S81694 administered intravenously in adult patients with advanced, metastatic solid tumours.
Schöffski, Patrick; Awada, Ahmad; de la Bigne, Anne-Marie; Felloussi, Zakia; Burbridge, Mike; Cantero, Frederique; Colombo, Riccardo; Maruzzelli, Sara; Ammattatelli, Katia; de Jonge, Maja; Aftimos, Philippe; Dumez, Herlinde; Sleijfer, Stefan.
Affiliation
  • Schöffski P; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium. Electronic address: patrick.schoffski@uzleuven.be.
  • Awada A; Clinical Trials Conduct Unit, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • de la Bigne AM; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France.
  • Felloussi Z; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France.
  • Burbridge M; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France.
  • Cantero F; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France.
  • Colombo R; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy.
  • Maruzzelli S; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy.
  • Ammattatelli K; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy.
  • de Jonge M; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Aftimos P; Clinical Trials Conduct Unit, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Dumez H; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium.
  • Sleijfer S; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Eur J Cancer ; 169: 135-145, 2022 07.
Article in En | MEDLINE | ID: mdl-35567919
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Anemia / Kidney Neoplasms / Neoplasms / Antineoplastic Agents Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Humans Language: En Journal: Eur J Cancer Year: 2022 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Anemia / Kidney Neoplasms / Neoplasms / Antineoplastic Agents Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Humans Language: En Journal: Eur J Cancer Year: 2022 Document type: Article Country of publication: