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Impact of duration of critical illness and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: A prospective, observational, cross-sectional human and two translational mouse studies.
Téblick, Arno; Van Dyck, Lisa; Van Aerde, Nathalie; Van der Perre, Sarah; Pauwels, Lies; Derese, Inge; Debaveye, Yves; Wouters, Pieter J; Vanhorebeek, Ilse; Langouche, Lies; Van den Berghe, Greet.
Affiliation
  • Téblick A; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Van Dyck L; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Van Aerde N; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Van der Perre S; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Pauwels L; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Derese I; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Debaveye Y; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Wouters PJ; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Vanhorebeek I; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Langouche L; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Van den Berghe G; Clinical division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. Electronic address: greet.vandenberghe@kuleuven.be.
EBioMedicine ; 80: 104057, 2022 Jun.
Article in En | MEDLINE | ID: mdl-35584557

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Glucocorticoid / Glucocorticoids Type of study: Observational_studies / Prevalence_studies Limits: Animals / Humans Language: En Journal: EBioMedicine Year: 2022 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Glucocorticoid / Glucocorticoids Type of study: Observational_studies / Prevalence_studies Limits: Animals / Humans Language: En Journal: EBioMedicine Year: 2022 Document type: Article Affiliation country: