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Assessing the Need for Semantic Data Integration for Surgical Biobanks-A Knowledge Representation Perspective.
Brochhausen, Mathias; Whorton, Justin M; Zayas, Cilia E; Kimbrell, Monica P; Bost, Sarah J; Singh, Nitya; Brochhausen, Christoph; Sexton, Kevin W; Blobel, Bernd.
Affiliation
  • Brochhausen M; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Whorton JM; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Zayas CE; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Kimbrell MP; Trauma Performance Improvement Coordinator, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Bost SJ; Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL 32611, USA.
  • Singh N; Department of Animal Sciences, University of Florida, Gainesville, FL 32611, USA.
  • Brochhausen C; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32611, USA.
  • Sexton KW; Central Biobank, Institute of Pathology, University and University Clinic of Regensburg, 93053 Regensburg, Germany.
  • Blobel B; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
J Pers Med ; 12(5)2022 May 07.
Article in En | MEDLINE | ID: mdl-35629179
ABSTRACT
To improve patient outcomes after trauma, the need to decrypt the post-traumatic immune response has been identified. One prerequisite to drive advancement in understanding that domain is the implementation of surgical biobanks. This paper focuses on the outcomes of patients with one of two diagnoses post-traumatic arthritis and osteomyelitis. In creating surgical biobanks, currently, many obstacles must be overcome. Roadblocks exist around scoping of data that is to be collected, and the semantic integration of these data. In this paper, the generic component model and the Semantic Web technology stack are used to solve issues related to data integration. The results are twofold (a) a scoping analysis of data and the ontologies required to harmonize and integrate it, and (b) resolution of common data integration issues in integrating data relevant to trauma surgery.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pers Med Year: 2022 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pers Med Year: 2022 Document type: Article Affiliation country: