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CRISPR/Cas9 editing of the MYO7A gene in rhesus macaque embryos to generate a primate model of Usher syndrome type 1B.
Ryu, Junghyun; Statz, John P; Chan, William; Burch, Fernanda C; Brigande, John V; Kempton, Beth; Porsov, Edward V; Renner, Lauren; McGill, Trevor; Burwitz, Benjamin J; Hanna, Carol B; Neuringer, Martha; Hennebold, Jon D.
Affiliation
  • Ryu J; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Statz JP; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Chan W; Division of Biological Sciences, University of Montana, Missoula, MT, 59812, USA.
  • Burch FC; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Brigande JV; University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.
  • Kempton B; Assisted Reproductive Technologies Core, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Porsov EV; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health and Science University, Portland, OR, 97239, USA.
  • Renner L; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health and Science University, Portland, OR, 97239, USA.
  • McGill T; Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health and Science University, Portland, OR, 97239, USA.
  • Burwitz BJ; Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Hanna CB; Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Neuringer M; Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Hennebold JD; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
Sci Rep ; 12(1): 10036, 2022 06 16.
Article in En | MEDLINE | ID: mdl-35710827

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Usher Syndromes Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Usher Syndromes Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: